The difference between a prospective and a retrospective study is whether the study identifies participants before the outcome has occurred or after. Prospective and retrospective studies typically are observational studies, with very few exceptions.
A prospective study identifies its sample population, often by some shared trait or characteristic, then follows them to see if in the future the outcome researchers are interested in develops.
Research process in a prospective study:
Example:
We used the records from Example Hospital to find patients recently diagnosed with type 2 diabetes who either did or did not receive a referral to a nutritionist. We followed those patients' records for 2 years, looking at their A1C and blood sugar numbers. We found that being referred to a nutritionist had a significant impact, as patients referred typically had lower A1C and blood sugar numbers than those who were not referred.
A retrospective study identifies it's sample population by the presence of the outcome the researchers are interested in, then they look back to see what commonalities this group shares.
Research process in a retrospective study:
Example:
We used the records from Example Hospital to identify patients who experienced a catheter associated urinary tract infection in our med surg unit. We looked at the records of their vitals at time of admission and what care they received while here to identify if there were any common factors that could be a cause. We found that catheter associated urinary tract infections were associated with having a catheter in for longer than 48 hrs, patient age >68 yrs, and diabetes.